Saturday, July 7, 2012

Nerve muscle III


  1. Name the protein that is embedded in the sarcoplasmic reticular membrane
Ryanodine receptor

  1. Name the type of nerves that innervate skeletal muscle fibres
Alpha motor neurons / somatic efferent neurons

  1. Name the region in a skeletal muscle fibre membrane that lies under the terminal portion of its axon.
Motor-and plate

  1. What is the local depolarization of motor-end-plate known  as?
Motor-ends-plate potential (MEPP)

  1. Name an ecetylcholine receptor blocker at the neuromuscular junction
Curare

  1. Name the specific acetylcholine receptors to which the chemical curare binds to
Nicotinic receptors

  1. Name a drug that is used in surgical procedures that mimicks the effects of curare
Gallamine (Tubocurarine)

  1. What is the specific action of ‘nerve gases’ in neuromuscular transmission that is used in biological warfare?
Inhibits acetylcholine esterase enzyme

  1. Name a toxin that blocks  the release of acetylcholine from nerve terminals.
Botullinum toxin

  1. What is the mechanical response of a single muscle fibre to a single action potential known as?
Muscle twitch

  1. Name the interval in a muscle twitch response that falls prior to the contraction period.
Latent-period

  1. What is the site of fatigue in a nerve-muscle preparation?
The neuro-muscular-junction (NMJ)

  1. What  are oxidative muscle fibres?
Fibres containing many mitochondria with high oxidative phosphorylation ability

  1. Name the oxygen-binding protein that is present in muscle fibres.
Myoglobin

  1. If neurons to a skeletal muscle  fibre are destroyed, the muscle becomes progressively smaller. What is this condition known as?
Atrophy


( Physiology; UMS 2008 )

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